Union Public Service Commission

Combined Medical Services Exam, 2014

General Ability, General Medicine & Paediatrics Paper I

Exam Name: Combined Medical Services Exam

Year: 2014

File Size: 945 KB

File Type: PDF

1. A patient with small cell lung carcinoma has symptomatic hyponatraemia (serum sodium 127 mmol/ L). The most likely etiology is:

(a) Fanconi Syndrome
(b) Cushing’s Syndrome
(c) Metabolic Syndrome
(d) Syndrome of inappropriate ADH

2. Regarding Gilbert’s syndrome, which one of the following statements is not correct?

(a) Jaundice becomes severe with time.
(b) Hyperbilirubinemia increases after fasting.
(c) Inheritance of disease is autosomal dominant.
(d) Liver histology is normal.

3. Which of the following is an uncommon cause of autonomic dysfunction?

(a) G B S (Guillain Barre Syndrome).
(b) Porphyria.
(c) Diabetic neuropathy.
(d) Neuropathy associated with Vitamin B12 deficiency.

4. Peripheral Eosinophilia is not a characteristic feature of:

(a) Hypersensitivity pneumonitis.
(b) Allergic aspergillosis.
(c) Tropical eosinophilia.
(d) Loeffler’s syndrome.

5. Salicylate intoxication in adults usually causes:

1. Severe respiratory alkalosis.
2. Mixed metabolic acidosis respiratory alkalosis.
3. Hyperchloremic metabolic acidosis.

Select the correct answer using the code given below

(a) 1 and 2 only
(b) 3 only
(c) 2 and 3 only
(d) 1, 2 and 3

6. With reference to psoriatic arthritis, which one of the following statements is not correct?

(a) In 70 – 80% patients psoriasis precedes arthritis.
(b) Distribution of arthritis is mainly asymmetrical.
(c) Involvement of PIP joints is more than DIP joints.
(d) Cup like erosions are seen on X ray.

7. Consider the following statements regarding rheumatic heart disease:

1. Rheumatic carditis is a pancarditis.
2. Carey–Coombs murmur is a delayed systolic murmur heard during the course of acute rheumatic fever.
3. Mitral regurgitation is the most common manifestation of acute rheumatic carditis.

Which of the statements given above is/are correct?

(a) 1 only
(b) 2 and 3
(c) 1 and 2
(d) 1 and 3

8. The extra cellular fluid deficit in a comatose patient of diabetic ketoacidosis is replenished by:

(a) 0.9 % NaCl
(b) 3 % NaCl
(c) 5 % Dextrose
(d) Ringer’s lactate

9. Which one of the following is not associated with a high reticulocyte count?

(a) Acute bleed
(b) Haemolytic anaemia
(c) Megaloblastic anaemia
(d) Response to treatment in ‘nutrition – deficiency’ anaemia

10. What happens when normal erythrocytes (blood – group matched) are transfused into a patient with anaemia secondary to an intracorpuscular defect?

(a) Donor cells are destroyed.
(b) Donor cells have normal survival.
(c) Depends on the severity of anaemia.
(d) Depends on whether the donor cells are fresh or stored (older than a week).

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